Associated TP15: Bioactive lipid mediaters in blistering autoimmune dermatoses

Bioactive lipid mediators are considered pivotal choreographers of all stages of immune responses. In line with this notion, targeting lipid mediators pharmacologically has often been meeting with success in the treatment of autoimmune diseases. The role of lipid mediators in the pathogenesis of autoimmune dermatoses, however, still remains largely elusive. More insights into their effects in the pathogenesis of these disease entities will be key for the successful development of new therapeutic strategies engaging the metabolism of lipid mediators.

My lab is dedicated to elucidate the role of lipid mediators in autoimmune dermatoses. Therefore, in the associated TP17 of the GRK1727 we are seeking to clarify the role of eicosanoids in the development of difficult-to-treat blistering autoimmune dermatoses, such as epidermolysis bullosa acquisita (EBA) and bullous pemphigoid (BP).

Tanya Sezin received her Dr. rer. nat. degree in 06/2016.