Dr. rer.nat. Yask Gupta


Lübeck Institute of Expermental Dermatology (LIED)
University of Lübeck
Ratzeburger Allee 160
23562 Lübeck

Email:
Phone:
+49 451 500 50887
Fax:
+49 451 500 50888

Publications

2019

  • Thieme, M., Bieber, K., Sezin, T., Wannick, M., Gupta, Y., Kalies, K., Ludwig, R. J., Mousavi, S., Zillikens, D. and Sadik, C. D.: The Sphingosine-1-Phosphate Receptor Modulator Fingolimod Aggravates Murine Epidermolysis Bullosa Acquisita J. Invest. Dermatol., n, 2019
    BibTeX Pubmed Auszeichnung
    % 31176709 
    @Article{pmid31176709,
       Author="Thieme, M.  and Bieber, K.  and Sezin, T.  and Wannick, M.  and Gupta, Y.  and Kalies, K.  and Ludwig, R. J.  and Mousavi, S.  and Zillikens, D.  and Sadik, C. D. ",
       Title="{{T}he {S}phingosine-1-{P}hosphate {R}eceptor {M}odulator {F}ingolimod {A}ggravates {M}urine {E}pidermolysis {B}ullosa {A}cquisita}",
       Journal="J. Invest. Dermatol.",
       Year="2019",
       Month="Jun"
    }
  • Vorobyev, A., Gupta, Y., Sezin, T., Koga, H., Bartsch, Y. C., Belheouane, M., Kunzel, S., Sina, C., Schilf, P., Korber-Ahrens, H., Beltsiou, F., Lara Ernst, A., Khil`chenko, S., Al-Aasam, H., Manz, R. A., Diehl, S., Steinhaus, M., Jascholt, J., Kouki, P., Boehncke, W. H., Mayadas, T. N., Zillikens, D., Sadik, C. D., Nishi, H., Ehlers, M., Moller, S., Bieber, K., Baines, J. F., Ibrahim, S. M. and Ludwig, R. J.: Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line Nat Commun, vol. 10, no. 1, pp. 4097, p, 2019
    BibTeX Pubmed Auszeichnung
    % 31506438 
    @Article{pmid31506438,
       Author="Vorobyev, A.  and Gupta, Y.  and Sezin, T.  and Koga, H.  and Bartsch, Y. C.  and Belheouane, M.  and Kunzel, S.  and Sina, C.  and Schilf, P.  and Korber-Ahrens, H.  and Beltsiou, F.  and Lara Ernst, A.  and Khil'chenko, S.  and Al-Aasam, H.  and Manz, R. A.  and Diehl, S.  and Steinhaus, M.  and Jascholt, J.  and Kouki, P.  and Boehncke, W. H.  and Mayadas, T. N.  and Zillikens, D.  and Sadik, C. D.  and Nishi, H.  and Ehlers, M.  and Moller, S.  and Bieber, K.  and Baines, J. F.  and Ibrahim, S. M.  and Ludwig, R. J. ",
       Title="{{G}ene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line}",
       Journal="Nat Commun",
       Year="2019",
       Volume="10",
       Number="1",
       Pages="4097",
       Month="Sep"
    }
    

2018

  • Hirose, M., Schilf, P., Gupta, Y., Zarse, K., Kunstner, A., Fahnrich, A., Busch, H., Yin, J., Wright, M. N., Ziegler, A., Vallier, M., Belheouane, M., Baines, J. F., Tautz, D., Johann, K., Oelkrug, R., Mittag, J., Lehnert, H., Othman, A., Johren, O., Schwaninger, M., Prehn, C., Adamski, J., Shima, K., Rupp, J., Hasler, R., Fuellen, G., Kohling, R., Ristow, M. and Ibrahim, S. M.: Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice Sci Rep, vol. 8, no. 1, pp. 5872, r, 2018
    BibTeX Pubmed Auszeichnung
    % 29651131 
    @Article{pmid29651131,
       Author="Hirose, M.  and Schilf, P.  and Gupta, Y.  and Zarse, K.  and Kunstner, A.  and Fahnrich, A.  and Busch, H.  and Yin, J.  and Wright, M. N.  and Ziegler, A.  and Vallier, M.  and Belheouane, M.  and Baines, J. F.  and Tautz, D.  and Johann, K.  and Oelkrug, R.  and Mittag, J.  and Lehnert, H.  and Othman, A.  and Johren, O.  and Schwaninger, M.  and Prehn, C.  and Adamski, J.  and Shima, K.  and Rupp, J.  and Hasler, R.  and Fuellen, G.  and Kohling, R.  and Ristow, M.  and Ibrahim, S. M. ",
       Title="{{L}ow-level mitochondrial heteroplasmy modulates {D}{N}{A} replication, glucose metabolism and lifespan in mice}",
       Journal="Sci Rep",
       Year="2018",
       Volume="8",
       Number="1",
       Pages="5872",
       Month="Apr"
    }

2017

  • Hirose, M., Schilf, P., Rohde, S., Gupta, Y., Sancerni, T., Alves-Guerra, M. C., Sina, C., Jaster, R., Miroux, B. and Ibrahim, S. M.: The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice Mitochondrion, v, 2017
    BibTeX Pubmed Auszeichnung
    % 29154852 
    @Article{pmid29154852,
       Author="Hirose, M.  and Schilf, P.  and Rohde, S.  and Gupta, Y.  and Sancerni, T.  and Alves-Guerra, M. C.  and Sina, C.  and Jaster, R.  and Miroux, B.  and Ibrahim, S. M. ",
       Title="{{T}he mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice}",
       Journal="Mitochondrion",
       Year="2017",
       Month="Nov"
    }
    
    
  • Sezin, T., Krajewski, M., Wutkowski, A., Mousavi, S., Chakievska, L., Bieber, K., Ludwig, R. J., Dahlke, M., Rades, D., Schulze, F. S., Schmidt, E., Kalies, K., Gupta, Y., Schilf, P., Ibrahim, S. M., Konig, P., Schwudke, D., Zillikens, D. and Sadik, C. D.: The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita J. Invest. Dermatol., vol. 137, no. 5, pp. 1104-1113, y, 2017
    BibTeX Pubmed Auszeichnung
    @Article{pmid28108297,
       Author="Sezin, T.  and Krajewski, M.  and Wutkowski, A.  and Mousavi, S.  and Chakievska, L.  and Bieber, K.  and Ludwig, R. J.  and Dahlke, M.  and Rades, D.  and Schulze, F. S.  and Schmidt, E.  and Kalies, K.  and Gupta, Y.  and Schilf, P.  and Ibrahim, S. M.  and Konig, P.  and Schwudke, D.  and Zillikens, D.  and Sadik, C. D. ",
       Title="{{T}he {L}eukotriene {B}4 and its {R}eceptor {B}{L}{T}1 {A}ct as {C}ritical {D}rivers of {N}eutrophil {R}ecruitment in {M}urine {B}ullous {P}emphigoid-{L}ike {E}pidermolysis {B}ullosa {A}cquisita}",
       Journal="J. Invest. Dermatol.",
       Year="2017",
       Volume="137",
       Number="5",
       Pages="1104--1113",
       Month="May"
    }
    
  • Sezin, T., Vorobyev, A., Sadik, C. D., Zillikens, D., Gupta, Y. and Ludwig, R. J.: Gene Expression Analysis Reveals Novel Shared Gene Signatures and Candidate Molecular Mechanisms between Pemphigus and Systemic Lupus Erythematosus in CD4+ T Cells Front Immunol, vol. 8, pp. 92, 2017
    BibTeX Pubmed Auszeichnung
    @Article{pmid29387060,
       Author="Sezin, T.  and Vorobyev, A.  and Sadik, C. D.  and Zillikens, D.  and Gupta, Y.  and Ludwig, R. J. ",
       Title="{{G}ene {E}xpression {A}nalysis {R}eveals {N}ovel {S}hared {G}ene {S}ignatures and {C}andidate {M}olecular {M}echanisms between {P}emphigus and {S}ystemic {L}upus {E}rythematosus in {C}{D}4+ {T} {C}ells}",
       Journal="Front Immunol",
       Year="2017",
       Volume="8",
       Pages="1992"
    }
    
    
    

2016

  • Hirose, M., Schilf, P., Gupta, Y., Wright, M. N., Wright, M. N., Johren, O., Wagner, A. E., Sina, C., Ziegler, A., Ristow, M. and Ibrahim, S. M.: Lifespan effects of mitochondrial mutations Nature, vol. 540, no. 7633, pp. E13-E14, 2016
    BibTeX Pubmed Auszeichnung
    @Article{pmid27974775,
       Author="Hirose, M.  and Schilf, P.  and Gupta, Y.  and Wright, M. N.  and Wright, M. N.  and Johren, O.  and Wagner, A. E.  and Sina, C.  and Ziegler, A.  and Ristow, M.  and Ibrahim, S. M. ",
       Title="{{L}ifespan effects of mitochondrial mutations}",
       Journal="Nature",
       Year="2016",
       Volume="540",
       Number="7633",
       Pages="E13-E14",
       Month="12"
    }
    
  • Gupta, Y., Moller, S., Witte, M., Belheouane, M., Sezin, T., Hirose, M., Vorobyev, A., Niesar, F., Bischof, J., Ludwig, R. J., Zillikens, D., Sadik, C. D., Restle, T., Hasler, R., Baines, J. F. and Ibrahim, S. M.: Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease BMC Genomics, vol. 17, pp. 2, 2016
    BibTeX Pubmed Auszeichnung
    @Article{pmid26879236,
       Author="Gupta, Y.  and Moller, S.  and Witte, M.  and Belheouane, M.  and Sezin, T.  and Hirose, M.  and Vorobyev, A.  and Niesar, F.  and Bischof, J.  and Ludwig, R. J.  and Zillikens, D.  and Sadik, C. D.  and Restle, T.  and Hasler, R.  and Baines, J. F.  and Ibrahim, S. M. ",
       Title="{{D}issecting genetics of cutaneous mi{R}{N}{A} in a mouse model of an autoimmune blistering disease}",
       Journal="BMC Genomics",
       Year="2016",
       Volume="17",
       Pages="112"
    }

2015

  • Sadeghi, H., Gupta, Y., Moller, S., Samavedam, U. K., Behnen, M., Kasprick, A., Bieber, K., Muller, S., Kalies, K., de Castro Marques, A., Recke, A., Schmidt, E., Zillikens, D., Laskay, T., Mariani, J., Ibrahim, S. M. and Ludwig, R. J.: The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita J. Pathol., vol. 237, no. 1, pp. 111-122, p, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25953430,
       Author="Sadeghi, H.  and Gupta, Y.  and Moller, S.  and Samavedam, U. K.  and Behnen, M.  and Kasprick, A.  and Bieber, K.  and Muller, S.  and Kalies, K.  and de Castro Marques, A.  and Recke, A.  and Schmidt, E.  and Zillikens, D.  and Laskay, T.  and Mariani, J.  and Ibrahim, S. M.  and Ludwig, R. J. ",
       Title="{{T}he retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita}",
       Journal="J. Pathol.",
       Year="2015",
       Volume="237",
       Number="1",
       Pages="111--122",
       Month="Sep"
    }
  • Iwata, H., Witte, M., Samavedam, U. K., Gupta, Y., Shimizu, A., Ishiko, A., Schroder, T., Seeger, K., Dahlke, M., Rades, D., Zillikens, D. and Ludwig, R. J.: Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita J. Immunol., vol. 195, no. 5, pp. 1945-1954, p, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid26202985,
       Author="Iwata, H.  and Witte, M.  and Samavedam, U. K.  and Gupta, Y.  and Shimizu, A.  and Ishiko, A.  and Schroder, T.  and Seeger, K.  and Dahlke, M.  and Rades, D.  and Zillikens, D.  and Ludwig, R. J. ",
       Title="{{R}adiosensitive {H}ematopoietic {C}ells {D}etermine the {E}xtent of {S}kin {I}nflammation in {E}xperimental {E}pidermolysis {B}ullosa {A}cquisita}",
       Journal="J. Immunol.",
       Year="2015",
       Volume="195",
       Number="5",
       Pages="1945--1954",
       Month="Sep"
    }
  • Vorobyev, A., Ujiie, H., Recke, A., Buijsrogge, J. J., Jonkman, M. F., Pas, H. H., Iwata, H., Hashimoto, T., Kim, S. C., Hoon Kim, J., Groves, R., Samavedam, U., Gupta, Y., Schmidt, E., Zillikens, D., Shimizu, H. and Ludwig, R. J.: Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters J. Invest. Dermatol., b, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25689103,
       Author="Vorobyev, A.  and Ujiie, H.  and Recke, A.  and Buijsrogge, J. J.  and Jonkman, M. F.  and Pas, H. H.  and Iwata, H.  and Hashimoto, T.  and Kim, S. C.  and Hoon Kim, J.  and Groves, R.  and Samavedam, U.  and Gupta, Y.  and Schmidt, E.  and Zillikens, D.  and Shimizu, H.  and Ludwig, R. J. ",
       Title="{{A}utoantibodies to {M}ultiple {E}pitopes on the {N}on-{C}ollagenous-1 {D}omain of {T}ype {V}{I}{I} {C}ollagen {I}nduce {B}listers}",
       Journal="J. Invest. Dermatol.",
       Year="2015",
       Pages=" ",
       Month="Feb"
  • Huebbe, P., Dose, J., Schloesser, A., Campbell, G., Gluer, C. C., Gupta, Y., Ibrahim, S., Minihane, A. M., Baines, J. F., Nebel, A. and Rimbach, G.: Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice Mol Nutr Food Res, vol. 59, no. 2, pp. 334-343, b, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25381750,
       Author="Huebbe, P.  and Dose, J.  and Schloesser, A.  and Campbell, G.  and Gluer, C. C.  and Gupta, Y.  and Ibrahim, S.  and Minihane, A. M.  and Baines, J. F.  and Nebel, A.  and Rimbach, G. ",
       Title="{{A}polipoprotein {E} ({A}{P}{O}{E}) genotype regulates body weight and fatty acid utilization-{S}tudies in gene-targeted replacement mice}",
       Journal="Mol Nutr Food Res",
       Year="2015",
       Volume="59",
       Number="2",
       Pages="334--343",
       Month="Feb"
  • van Beek, N., Patsatsi, A., Gupta, Y., Moller, S., Freitag, M., Lemcke, S., Recke, A., Zillikens, D., Schmidt, E. and Ibrahim, S.: A family with atypical Hailey Hailey disease-is there more to the underlying genetics than ATP2C1? PLoS ONE, vol. 10, no. 4, pp. 121253, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25837627,
       Author="van Beek, N.  and Patsatsi, A.  and Gupta, Y.  and Moller, S.  and Freitag, M.  and Lemcke, S.  and Recke, A.  and Zillikens, D.  and Schmidt, E.  and Ibrahim, S. ",
       Title="{{A} family with atypical {H}ailey {H}ailey disease--is there more to the underlying genetics than {A}{T}{P}2{C}1?}",
       Journal="PLoS ONE",
       Year="2015",
       Volume="10",
       Number="4",
       Pages="e0121253"
    }

2014

  • Gupta, Y., Witte, M., Moller, S., Ludwig, R. J., Restle, T., Zillikens, D. and Ibrahim, S. M.: ptRNApred: computational identification and classification of post-transcriptional RNA Nucleic Acids Res., vol. 42, no. 22, pp. e167, c, 2014
    BibTeX Pubmed Auszeichnung
    @Article{pmid25303994,
       Author="Gupta, Y.  and Witte, M.  and Moller, S.  and Ludwig, R. J.  and Restle, T.  and Zillikens, D.  and Ibrahim, S. M. ",
       Title="{pt{R}{N}{A}pred: computational identification and classification of post-transcriptional {R}{N}{A}}",
       Journal="Nucleic Acids Res.",
       Year="2014",
       Volume="42",
       Number="22",
       Pages="e167",
       Month="Dec"
    }
    

2013

  • Samavedam, U. K., Kalies, K., Scheller, J., Sadeghi, H., Gupta, Y., Jonkman, M. F., Schmidt, E., Westermann, J., Zillikens, D., Rose-John, S. and Ludwig, R. J.: Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction J. Autoimmun., vol. 40, pp. 74-85, b, 2013
    BibTeX Pubmed Auszeichnung
    @Article{pmid22980031,
       Author="Samavedam, U. K.  and Kalies, K.  and Scheller, J.  and Sadeghi, H.  and Gupta, Y.  and Jonkman, M. F.  and Schmidt, E.  and Westermann, J.  and Zillikens, D.  and Rose-John, S.  and Ludwig, R. J. ",
       Title="{{R}ecombinant {I}{L}-6 treatment protects mice from organ specific autoimmune disease by {I}{L}-6 classical signalling-dependent {I}{L}-1ra induction}",
       Journal="J. Autoimmun.",
       Year="2013",
       Volume="40",
       Pages="74--85",
       Month="Feb"
  • Gupta, Y., Moller, S., Zillikens, D., Boehncke, W. H., Ibrahim, S. M. and Ludwig, R. J.: Genetic control of psoriasis is relatively distinct from that of metabolic syndrome and coronary artery disease Exp. Dermatol., vol. 22, no. 8, pp. 552-553, g, 2013
    BibTeX Pubmed Auszeichnung
    @Article{pmid23879815,
       Author="Gupta, Y.  and Moller, S.  and Zillikens, D.  and Boehncke, W. H.  and Ibrahim, S. M.  and Ludwig, R. J. ",
       Title="{{G}enetic control of psoriasis is relatively distinct from that of metabolic syndrome and coronary artery disease}",
       Journal="Exp. Dermatol.",
       Year="2013",
       Volume="22",
       Number="8",
       Pages="552--553",
       Month="Aug"

2012

  • Kasperkiewicz, M., Nimmerjahn, F., Wende, S., Hirose, M., Iwata, H., Jonkman, M. F., Samavedam, U., Gupta, Y., Moller, S., Rentz, E., Hellberg, L., Kalies, K., Yu, X., Schmidt, E., Hasler, R., Laskay, T., Westermann, J., Kohl, J., Zillikens, D. and Ludwig, R. J.: Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury J. Pathol., vol. 228, no. 1, pp. 8-19, p, 2012
    BibTeX Pubmed Auszeichnung
    @Article{pmid22430937,
       Author="Kasperkiewicz, M.  and Nimmerjahn, F.  and Wende, S.  and Hirose, M.  and Iwata, H.  and Jonkman, M. F.  and Samavedam, U.  and Gupta, Y.  and Moller, S.  and Rentz, E.  and Hellberg, L.  and Kalies, K.  and Yu, X.  and Schmidt, E.  and Hasler, R.  and Laskay, T.  and Westermann, J.  and Kohl, J.  and Zillikens, D.  and Ludwig, R. J. ",
       Title="{{G}enetic identification and functional validation of {F}cγ{R}{I}{V} as key molecule in autoantibody-induced tissue injury}",
       Journal="J. Pathol.",
       Year="2012",
       Volume="228",
       Number="1",
       Pages="8--19",
       Month="Sep"