Dr. rer. nat. Unni Samavedam


Dept. of Dermatology
University of Lübeck
Ratzeburger Allee 160
23562 Lübeck

Email:
Phone:
+49 451 500 3254
Fax:
+49 451 500 6595

Publications

2016

  • Hirose, M., Kasprick, A., Beltsiou, F., Dieckhoff Schulze, K., Schulze, F. S., Samavedam, U. K., Hundt, J. E., Pas, H. H., Jonkman, M. F., Schmidt, E., Kalies, K., Zillikens, D., Ludwig, R. J. and Bieber, K.: Reduced skin blistering in experimental epidermolysis bullosa acquisita after anti-TNF treatment Mol. Med., vol. 23, c, 2016
    BibTeX
    @Article{pmid27999842,
       Author="Hirose, M.  and Kasprick, A.  and Beltsiou, F.  and Dieckhoff Schulze, K.  and Schulze, F. S.  and Samavedam, U. K.  and Hundt, J. E.  and Pas, H. H.  and Jonkman, M. F.  and Schmidt, E.  and Kalies, K.  and Zillikens, D.  and Ludwig, R. J.  and Bieber, K. ",
       Title="{{R}educed skin blistering in experimental epidermolysis bullosa acquisita after anti-{T}{N}{F} treatment}",
       Journal="Mol. Med.",
       Year="2016",
       Volume="23",
       Month="Dec"
    }

2015

  • Sadeghi, H., Gupta, Y., Moller, S., Samavedam, U. K., Behnen, M., Kasprick, A., Bieber, K., Muller, S., Kalies, K., de Castro Marques, A., Recke, A., Schmidt, E., Zillikens, D., Laskay, T., Mariani, J., Ibrahim, S. M. and Ludwig, R. J.: The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita J. Pathol., vol. 237, no. 1, pp. 111-122, p, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25953430,
       Author="Sadeghi, H.  and Gupta, Y.  and Moller, S.  and Samavedam, U. K.  and Behnen, M.  and Kasprick, A.  and Bieber, K.  and Muller, S.  and Kalies, K.  and de Castro Marques, A.  and Recke, A.  and Schmidt, E.  and Zillikens, D.  and Laskay, T.  and Mariani, J.  and Ibrahim, S. M.  and Ludwig, R. J. ",
       Title="{{T}he retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita}",
       Journal="J. Pathol.",
       Year="2015",
       Volume="237",
       Number="1",
       Pages="111--122",
       Month="Sep"
    }
  • Iwata, H., Witte, M., Samavedam, U. K., Gupta, Y., Shimizu, A., Ishiko, A., Schroder, T., Seeger, K., Dahlke, M., Rades, D., Zillikens, D. and Ludwig, R. J.: Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita J. Immunol., vol. 195, no. 5, pp. 1945-1954, p, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid26202985,
       Author="Iwata, H.  and Witte, M.  and Samavedam, U. K.  and Gupta, Y.  and Shimizu, A.  and Ishiko, A.  and Schroder, T.  and Seeger, K.  and Dahlke, M.  and Rades, D.  and Zillikens, D.  and Ludwig, R. J. ",
       Title="{{R}adiosensitive {H}ematopoietic {C}ells {D}etermine the {E}xtent of {S}kin {I}nflammation in {E}xperimental {E}pidermolysis {B}ullosa {A}cquisita}",
       Journal="J. Immunol.",
       Year="2015",
       Volume="195",
       Number="5",
       Pages="1945--1954",
       Month="Sep"
    }
  • Tukaj, S., Hellberg, L., Ueck, C., Hansel, M., Samavedam, U., Zillikens, D., Ludwig, R., Laskay, T. and Kasperkiewicz, M.: Heat shock protein 90 is required for ex vivo neutrophil-driven autoantibody-induced tissue damage in experimental epidermolysis bullosa acquisita Exp. Dermatol., r, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25739426,
       Author="Tukaj, S.  and Hellberg, L.  and Ueck, C.  and Hansel, M.  and Samavedam, U.  and Zillikens, D.  and Ludwig, R.  and Laskay, T.  and Kasperkiewicz, M. ",
       Title="{{H}eat shock protein 90 is required for ex vivo neutrophil-driven autoantibody-induced tissue damage in experimental epidermolysis bullosa acquisita}",
       Journal="Exp. Dermatol.",
       Year="2015",
       Pages=" ",
       Month="Mar"
  • Sadeghi, H., Lockmann, A., Hund, A. C., Samavedam, U. K., Pipi, E., Vafia, K., Hauenschild, E., Kalies, K., Pas, H. H., Jonkman, M. F., Iwata, H., Recke, A., Schon, M. P., Zillikens, D., Schmidt, E. and Ludwig, R. J.: Caspase-1-Independent IL-1 Release Mediates Blister Formation in Autoantibody-Induced Tissue Injury through Modulation of Endothelial Adhesion Molecules J. Immunol., r, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25795756,
       Author="Sadeghi, H.  and Lockmann, A.  and Hund, A. C.  and Samavedam, U. K.  and Pipi, E.  and Vafia, K.  and Hauenschild, E.  and Kalies, K.  and Pas, H. H.  and Jonkman, M. F.  and Iwata, H.  and Recke, A.  and Schon, M. P.  and Zillikens, D.  and Schmidt, E.  and Ludwig, R. J. ",
       Title="{{C}aspase-1-{I}ndependent {I}{L}-1 {R}elease {M}ediates {B}lister {F}ormation in {A}utoantibody-{I}nduced {T}issue {I}njury through {M}odulation of {E}ndothelial {A}dhesion {M}olecules}",
       Journal="J. Immunol.",
       Year="2015",
       Pages=" ",
       Month="Mar"
    }
  • Vorobyev, A., Ujiie, H., Recke, A., Buijsrogge, J. J., Jonkman, M. F., Pas, H. H., Iwata, H., Hashimoto, T., Kim, S. C., Hoon Kim, J., Groves, R., Samavedam, U., Gupta, Y., Schmidt, E., Zillikens, D., Shimizu, H. and Ludwig, R. J.: Autoantibodies to Multiple Epitopes on the Non-Collagenous-1 Domain of Type VII Collagen Induce Blisters J. Invest. Dermatol., b, 2015
    BibTeX Pubmed Auszeichnung
    @Article{pmid25689103,
       Author="Vorobyev, A.  and Ujiie, H.  and Recke, A.  and Buijsrogge, J. J.  and Jonkman, M. F.  and Pas, H. H.  and Iwata, H.  and Hashimoto, T.  and Kim, S. C.  and Hoon Kim, J.  and Groves, R.  and Samavedam, U.  and Gupta, Y.  and Schmidt, E.  and Zillikens, D.  and Shimizu, H.  and Ludwig, R. J. ",
       Title="{{A}utoantibodies to {M}ultiple {E}pitopes on the {N}on-{C}ollagenous-1 {D}omain of {T}ype {V}{I}{I} {C}ollagen {I}nduce {B}listers}",
       Journal="J. Invest. Dermatol.",
       Year="2015",
       Pages=" ",
       Month="Feb"

2014

  • Samavedam, U. K., Iwata, H., Muller, S., Schulze, F. S., Recke, A., Schmidt, E., Zillikens, D. and Ludwig, R. J.: GM-CSF modulates autoantibody production and skin blistering in experimental epidermolysis bullosa acquisita J. Immunol., vol. 192, no. 2, pp. 559-571, n, 2014
    BibTeX Pubmed Auszeichnung
    @Article{pmid24337383,
       Author="Samavedam, U. K.  and Iwata, H.  and Muller, S.  and Schulze, F. S.  and Recke, A.  and Schmidt, E.  and Zillikens, D.  and Ludwig, R. J. ",
       Title="{{G}{M}-{C}{S}{F} modulates autoantibody production and skin blistering in experimental epidermolysis bullosa acquisita}",
       Journal="J. Immunol.",
       Year="2014",
       Volume="192",
       Number="2",
       Pages="559--571",
       Month="Jan"
    }
    
    

2013

  • Samavedam, U. K., Kalies, K., Scheller, J., Sadeghi, H., Gupta, Y., Jonkman, M. F., Schmidt, E., Westermann, J., Zillikens, D., Rose-John, S. and Ludwig, R. J.: Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction J. Autoimmun., vol. 40, pp. 74-85, b, 2013
    BibTeX Pubmed Auszeichnung
    @Article{pmid22980031,
       Author="Samavedam, U. K.  and Kalies, K.  and Scheller, J.  and Sadeghi, H.  and Gupta, Y.  and Jonkman, M. F.  and Schmidt, E.  and Westermann, J.  and Zillikens, D.  and Rose-John, S.  and Ludwig, R. J. ",
       Title="{{R}ecombinant {I}{L}-6 treatment protects mice from organ specific autoimmune disease by {I}{L}-6 classical signalling-dependent {I}{L}-1ra induction}",
       Journal="J. Autoimmun.",
       Year="2013",
       Volume="40",
       Pages="74--85",
       Month="Feb"
  • Hellberg, L., Samavedam, U. K., Holdorf, K., Hansel, M., Recke, A., Beckmann, T., Steinhorst, K., Boehncke, W. H., Kirchner, T., Mockel, N., Solbach, W., Zillikens, D., Schmidt, E., Ludwig, R. J. and Laskay, T.: Methylprednisolone Blocks Autoantibody-Induced Tissue Damage in Experimental Models of Bullous Pemphigoid and Epidermolysis Bullosa Acquisita through Inhibition of Neutrophil Activation J. Invest. Dermatol., vol. 133, no. 10, pp. 2390-2399, t, 2013
    BibTeX Pubmed Auszeichnung
    @Article{pmid23448878,
       Author="Hellberg, L.  and Samavedam, U. K.  and Holdorf, K.  and Hansel, M.  and Recke, A.  and Beckmann, T.  and Steinhorst, K.  and Boehncke, W. H.  and Kirchner, T.  and Mockel, N.  and Solbach, W.  and Zillikens, D.  and Schmidt, E.  and Ludwig, R. J.  and Laskay, T. ",
       Title="{{M}ethylprednisolone {B}locks {A}utoantibody-{I}nduced {T}issue {D}amage in {E}xperimental {M}odels of {B}ullous {P}emphigoid and {E}pidermolysis {B}ullosa {A}cquisita through {I}nhibition of {N}eutrophil {A}ctivation}",
       Journal="J. Invest. Dermatol.",
       Year="2013",
       Volume="133",
       Number="10",
       Pages="2390--2399",
       Month="Oct"

2012

  • Kasperkiewicz, M., Nimmerjahn, F., Wende, S., Hirose, M., Iwata, H., Jonkman, M. F., Samavedam, U., Gupta, Y., Moller, S., Rentz, E., Hellberg, L., Kalies, K., Yu, X., Schmidt, E., Hasler, R., Laskay, T., Westermann, J., Kohl, J., Zillikens, D. and Ludwig, R. J.: Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury J. Pathol., vol. 228, no. 1, pp. 8-19, p, 2012
    BibTeX Pubmed Auszeichnung
    @Article{pmid22430937,
       Author="Kasperkiewicz, M.  and Nimmerjahn, F.  and Wende, S.  and Hirose, M.  and Iwata, H.  and Jonkman, M. F.  and Samavedam, U.  and Gupta, Y.  and Moller, S.  and Rentz, E.  and Hellberg, L.  and Kalies, K.  and Yu, X.  and Schmidt, E.  and Hasler, R.  and Laskay, T.  and Westermann, J.  and Kohl, J.  and Zillikens, D.  and Ludwig, R. J. ",
       Title="{{G}enetic identification and functional validation of {F}cγ{R}{I}{V} as key molecule in autoantibody-induced tissue injury}",
       Journal="J. Pathol.",
       Year="2012",
       Volume="228",
       Number="1",
       Pages="8--19",
       Month="Sep"